The FLEMENGHO database

The database comprises 35 years of longitudinal research, both detailed clinical data as deep cardiovascular phenotyes. In addition, our rich biobank contains over 50.000 biological samples (blood and urine).

3 0 +
years of follow-up
0 +

Clinical information


Stethoscope heart
  • Demographics
  • Anthropometrics (incl. body composition)
  • Medical history
  • Medication use
  • Lifestyle (smoking, alcohol, physical activity, .. )
  • Clinical hematology and biochemistry
  • Proteomics (Olink Target CVDII)
  • Metabolomics
  • Genetics

Cardiovascular phenotypes

Blood pressure
  • Conventional BP (auscultation and oscillometry)
  • Home blood pressure
  • Ambulatory blood pressure
  • Conventional echo and TDI
  • 2D deformation (LV and LA), both peak values and time-series
  • 3D echocardiography
  • Diastolic stress (cycle ergometry)
Arterial stiffness and hemodynamics
  • Pulse Wave Analysis
  • Pulse Wave Velocity                  (carotid-femoral, carotid-radial)
Endothelial function
  • Flow-mediated slowing (EndoFMS)
  • Peripheral arterial reactivity (EndoPAR)
Cardiopulmonary exercise test
  • ECG, blood pressure, hemodynamics and gas exchange during exercise
  • Incl. stress echocardiography
  • CPET time-series also available
    • Ankle-brachial index (ABI)
    • Carotid intima-media thickness (cIMT)
    • Vascularisation: renal, retinal and sublingual


    Our biobank is under supervision of the UZ/KU Leuven Biobank and contains over 50.000 samples (serum, plasma, DNA and urine). 

    All samples are available for secondary analyses providing permission of the UZ/KU Leuven Biobank and an ethics committee / IRB.

    nl_BENederlands (België)